There is no highest limit for the liver enzymes index AST (SGOT), ALT (SGPT), and GGT. Depending on the type of disease, these stats will increase to a certain extent. Without timely support to improve the cause of elevated liver enzymes, these numbers can drop surprisingly low because no more liver cells survive.
I. What is AST (SGOT), ALT (SGPT), and GGT?
1. What is AST (SGOT)?
The normal level of AST (also known as SGOT) is between 20-40 UI / L. Besides AST, there is also ALT, which are two liver enzymes that are specific to the liver. When more liver cells are damaged or necrotic, both of these enzymes will be “freed” and massively released into the bloodstream.
2. What is ALT (SGPT)?
Compared with the AST index, ALT (also known as SGPT) is a specific index, warning more clearly the damage to the liver due to located mainly in liver cytoplasm (only a few in striatum muscle cells and heart). The AST enzyme, in addition to the liver, is also located in other organs, especially muscle. Normally, the ALT test is also in the range: 20-40 UI / L, equivalent to the average level of AST enzyme.
3. What is GGT indicator?
The GGT index (also known as Gamma GT) is the index of enzymes in the parietal cells of the bile duct. The normal GGT ratio is below 60 UI / L (male 11-50 UI / L, female 07-32 UI / L).
II. How high are the GGT, AST, and ALT scores?
Acute viral hepatitis (A, B, C, E, D …) or any other cause also causes a sudden increase in liver enzymes. The AST (SGOT), ALT (SGPT), and GGT index increase from 1-2 times in mild, from 2 to 5 times an increase in a moderate level and an increase of more than 5 times for a severe increase. . In many cases of acute hepatitis or fulminant hepatitis or liver cancer, the amount of liver enzymes increases dramatically, sometimes up to 5,000UI / L.
The amount of liver enzymes in the blood because the liver is damaged by alcohol, the AST index usually increases from 2 to 10 times while the ALT level increases slightly.
3. Supportive drugs improve
Adjuvants to improve a certain disease can also cause side effects that affect the liver’s metabolism or cause hepatocellular toxicity to develop acute drug-induced hepatitis, for example adjuvant poisoning. improve TB. In this case, the liver enzymes AST (SGOT), ALT (SGPT), and GGT can be as high as 3,000UI / L.
4. Acute liver failure or liver shock
One of the indicators AST (SGOT), ALT (SGPT), GGT of patients can increase to 5,000 UI / L.
5. In obstructive jaundice
The indicators such as AST (SGOT), ALT (SGPT), and GGT increase but are often below 500 UI / L.
6. Liver enzyme test
If GGT increases, it can be hepatitis, liver tumor, bile ducts, cirrhosis … GGT index also increases in case of heart failure or using antibiotics, antifungal drugs, pain relievers. anti-inflammatory … Besides, GGT is also a liver enzyme that indicates liver damage related to alcohol abuse in excess of the permitted level. Hepatic enzymes AST (SGOT), ALT (SGPT), and GGT increased in cases of malaria, biliary tract disease, iron overload, autoimmune hepatitis, small intestinal autoimmune disease, and some other diseases.